Characteristics of clinical Helicobacter pylori strains from Ecuador.

نویسندگان

  • Yvette J Debets-Ossenkopp
  • Germán Reyes
  • Janet Mulder
  • Birgit M aan de Stegge
  • José T A M Peters
  • Paul H M Savelkoul
  • J Tanca
  • Amado S Peña
  • Christina M J E Vandenbroucke-Grauls
چکیده

In Ecuador, Helicobacter pylori infections are highly prevalent. A total of 42 H. pylori clinical isolates from 86 patients attending the outpatient clinic of the gastroenterology department of the university hospital of Guayaquil in Ecuador were characterized. Their susceptibility, and cagA and vacA status were determined. Resistance to metronidazole and clarithromycin was found in 80.9% and 9.5% of strains, respectively. Neither amoxicillin- nor tetracycline-resistant strains were found. The most prevalent genotype was the cagA(+), vacA s1b,m1 type. This genotype was associated with gastric cancer and peptic ulcer. Typing by random amplified polymorphic DNA showed no genetic relationship among the strains.

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عنوان ژورنال:
  • The Journal of antimicrobial chemotherapy

دوره 51 1  شماره 

صفحات  -

تاریخ انتشار 2003